استیگماسترول سیگما 1 گرمی موجود S2424 Stigmasterol

The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada

SAFETY DATA SHEET
Version6.2
Revision Date02/24/2020
Print Date07/11/2021

SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1Product identifiers
Product name:Stigmasterol
Product Number:S2424
Brand:Sigma
CAS-No.:83-48-7
1.2Relevant identified uses of the substance or mixture and uses advised against
Identified uses:Laboratory chemicals, Synthesis of substances

1.3Details of the supplier of the safety data sheet
Company:Sigma-Aldrich Inc.
3050 SPRUCE ST
ST. LOUIS MO 63103
UNITED STATES
Telephone:+1 314 771-5765
Fax:+1 800 325-5052
1.4Emergency telephone number
Emergency Phone #:800-424-9300 CHEMTREC (USA) +1-703-
527-3887 CHEMTREC (International) 24
Hours/day; 7 Days/week


SECTION 2: Hazards identification
2.1Classification of the substance or mixture
Not a hazardous substance or mixture.
2.2GHS Label elements, including precautionary statements
Not a hazardous substance or mixture.
2.3Hazards not otherwise classified (HNOC) or not covered by GHS-none



SECTION 3: Composition/information on ingredients
3.1Substances
Synonyms:Stigmasterin
3β-Hydroxy-24-ethyl-5,22-cholestadiene
5,22-Stigmastadien-3β-ol

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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada

Formula:C29H48O
Molecular weight:412.69 g/mol
CAS-No.:83-48-7
EC-No.:201-482-7
No components need to be disclosed according to the applicable regulations.



SECTION 4: First aid measures
4.1De script ion of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2Most important symptoms and effects, both acute and  delay ed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures
5.1Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2Special hazards arising from the substance or mixture
Carbon oxides
5.3Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4Further information
No data available

SECTION 6: Accidental release measures
6.1Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapours, mist or gas.
For personal protection see section 8.
6.2Environmental precautions
No special environmental precautions required.
6.3Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.

Sigma-S2424Page3of8

The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada





6.4Reference to other sections
For disposal see section 13.



SECTION 7: Handling and storage
7.1Precautions for safe handling
Further processing of solid materials may result in the formation of combustible dusts. The
potential for combustible dust formation should be taken into consideration before
additional processing occurs.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
Storage class (TRGS 510): 11: Combustible Solids
7.3Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated



SECTION 8: Exposure controls/personal protection
8.1Control parameters
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
8.2Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
Full contact
Material: Nitrile rubber
Minimum layer thickness:0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness:0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de, test method: EN374

Sigma-S2424Page4of8



The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada



If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the CE approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Choose body protection in relation to its type, to the concentration and amount of
dangerous substances, and to the specific work-place., The type of protective
equipment must be select ed according to the concentration and amount of the
dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of
dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use
respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
No special environmental precautions required.


SECTION 9: Physical and chemical properties
9.1Information on basic physical and chemical properties
a)AppearanceForm: solid
b)OdourNo data available
c)Odour ThresholdNo data available
d)pHNo data available
e)Melting
point/freezing point
Melting point/range: 165 -167 °C(329 -333 °F)-lit.
f)Initial boiling point
and boiling range
No data available
g)Flash point()No data available
h)Evaporation rateNo data available
i)Flammability (solid,
gas)
No data available
j)Upper/lower
flammability or
explosive limit s
No data available
k)Vapour pressureNo data available
l)Vapour densityNo data available
m)Relative densityNo data available
n)Water solubilityNo data available
o)Partition coefficient:
n-octanol/water
No data available
p)Auto-ignition
temperature
No data available

Sigma-S2424Page5of8



The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada


q)Decomposition
temperature
No data available
r)ViscosityNo data available
s)Explosive propertiesNo data available
t)Oxidizing propertiesNo data available
9.2Other safety information
No data available



SECTION 10: Stability and reactivity
10.1Reactivity
No data available
10.2Chemical stability
Stable under recommended storage conditions.
10.3Possibility of hazardous reactions
No data available
10.4Conditions to avoid
No data available
10.5Incompatible materials
No data available
10.6Hazardous decomposition products
Hazardous decomposition products formed under fire conditions.-Carbon oxides
Other decomposition products-No data available
In the event of fire: see section 5


SECTION 11: Toxicological information
11.1Information on toxicological effects
Acute toxicity
Skin corrosion/irritation
Serious eye damage/eye irritation
Respiratory or skin sensitisation
Germ cell mutagenicity
Carcinogenicity
IARC:No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
NTP:No component of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
OSHA:No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.

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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada

Reproductive toxicity
Specific target organ toxicity -single exposure
Specific target organ toxicity -repeated exposure
Aspiration hazard
Additional Information
RTECS: Not available


To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.

SECTION 12: Ecological information
12.1Toxicity
12.2Persistence and degradability
12.3Bioaccumulative potential
12.4Mobility in soil
12.5 result s of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6Other adverse effects

SECTION 13: Disposal considerations
13.1Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information
DOT (US)
Not dangerous goods

IMDG
Not dangerous goods

IATA
Not dangerous goods

Sigma-S2424Page7of8

The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada

SECTION 15: Regulatory information

SARA 302 Components
No chemicals in this material are subject to the reporting requirements of SARA Title III,
Section 302.
SARA 313 Components
This material does not contain any chemical components with known CAS numbers that
exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section
313.
SARA 311/312 Hazards
No SARA Hazards
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.

No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
Stigmasta-5,22-dien-3-β-olCAS-No.
83-48-7

Revision Date

Stigmasta-5,22-dien-3-β-olCAS-No.
83-48-7

Revision Date

New Jersey Right To Know Components
Stigmasta-5,22-dien-3-β-olCAS-No.
83-48-7

Revision Date

SECTION 16: Other information
Further information
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make un limit ed paper copies
for internal use only.
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shallnot be held liable for any
damage result ing from handling or  from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further informationplease contact mlsbranding@sial.com.
Version: 6.2Revision Date: 02/24/2020Print Date: 07/11/2021

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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada