https://www.emdmillipore.com/US/en/product/Tryptic-Soy-agar,MDA_CHEM-105458
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
SAFETY DATA SHEET
Version 8.4
Revision Date 06/23/2021
Print Date 06/23/2021
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers
Product name : Tryptic Soy agar acc. EP, USP, JP, ISO and
FDA-BAM GranuCult®
Product Number : 1.05458
Catalogue No. : 105458
Brand : Millipore
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Biochemical research/analysis
Uses advised against : Reserved for industrial and professional use.
1.3 Details of the supplier of the safety data sheet
Company : EMD Millipore Corporation
400 Summit Drive
BURLINGTON MA 01803
UNITED STATES
Telephone : +1 800-645-5476
1.4 Emergency telephone
Emergency Phone # : 800-424-9300 CHEMTREC (USA) +1-703-
527-3887 CHEMTREC (International) 24
Hours/day; 7 Days/week
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin sensitization (Category 1), H317
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements
Pictogram
Signal word Warning
Hazard statement(s)
H317 May cause an allergic skin reaction.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
P272 Contaminated work clothing must not be allowed out of the
workplace.
P280 Wear protective gloves.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/ container to an approved waste disposal
plant.
2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none
SECTION 3: Composition/information on ingredients
3.2 Mixtures
Component Classification Concentration
Pyruvic acid sodium salt
CAS-No.
EC-No.
Registration
number
113-24-6
204-024-4
01-2120767047-50-
XXXX
Eye Irrit. 2A; Skin Sens.
1B; H319, H317
>= 1 - < 5 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1 De script ion of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delay ed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limit ations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Combustible.
Fire may cause evolution of:
Hydrogen chloride gas
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures,
consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.Tightly closed. Dry.
Recommended storage temperature see product label.
Storage class (TRGS 510): 11: Combustible Solids
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
8.2 Exposure controls
Appropriate engineering controls
Immediately change contaminated clothing. Apply preventive skin protection. Wash
hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: > 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: > 480 min
Material tested:KCL 741 Dermatril® L
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
Color: beige
b) Odor peptone-like
c) Odor Threshold No data available
d) pH 7.1 - 7.5 at 40 g/l at 25 °C (77 °F) - (after autoclaving)
e) Melting
point/freezing point
No data available
f) Initial boiling point
and boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid,
gas)
No data available
j) Upper/lower
flammability or
explosive limit s
No data available
k) Vapor pressure No data available
l) Vapor density No data available
m) Relative density No data available
n) Water solubility 40 g/l at 95 °C (203 °F)
o) Partition coefficient:
n-octanol/water
No data available
p) Autoignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Bulk density ca.620 kg/m3
SECTION 10: Stability and reactivity
10.1 Reactivity
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution, when whirled up a dust explosion potential may generally
be assumed.
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution, when whirled up a dust explosion potential may generally
be assumed.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature).
10.3 Possibility of hazardous reactions
Violent reactions possible with:
Strong oxidizing agents
10.4 Conditions to avoid
no information available
no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Mixture
Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitization
Mixture may cause an allergic skin reaction.
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
NTP: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Hazardous properties cannot be excluded but are unlikely when the product is handled
appropriately.
Components
Pyruvic acid sodium salt
Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Skin - reconstructed human epidermis (RhE)
result : No skin irritation - 42 min
(OECD Test Guideline 439)
Serious eye damage/eye irritation
Eyes - In vitro study
result : Causes serious eye irritation. - 6 h
(OECD Test Guideline 492)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
result : positive
(OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
result : negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Aspiration hazard
No data available
SECTION 12: Ecological information
12.1 Toxicity
Mixture
No data available
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 result s of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
No data available
Components
Pyruvic acid sodium salt
No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product
Waste material must be disposed of in accordance with the national and local regulations.
Leave chemicals in original containers. No mixing with other waste. Handle uncleaned
containers like the product itself. See www.retrologistik.com for processes regarding the
return of chemicals and containers, or contact us there if you have further questions.
SECTION 14: Transport information
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods
Further information
Not classified as dangerous in the meaning of transport regulations.
SECTION 15: Regulatory information
SARA 302 Components
This material does not contain any components with a section 302 EHS TPQ.
SARA 313 Components
Millipore - 1.05458
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The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
This material does not contain any chemical components with known CAS numbers that
exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section
313.
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
SECTION 16: Other information
Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage result ing from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make un limit ed paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact mlsbranding@sial.com.
Version: 8.4 Revision Date: 06/23/2021 Print Date: 06/23/2021
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