Version 8.1 Revision Date 01/25/2021 Print Date 02/14/2021

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1. 1. Product identifiers

Product name              : Polyethylene glycol dimethyl ether 500

(stabilised) for synthesis

Product Number            : 8.14171

Catalogue No.              : 814171

Brand                          : Millipore

CAS-No.                      : 24991-55-7

1. 2. Relevant identified uses of the substance or mixture and uses advised against

Identified uses              : Chemical for synthesis

1. 3. Details of the supplier of the safety data sheet

Company                    : EMD Millipore Corporation 400 Summit Drive

BURLINGTON MA 01803 UNITED STATES

Telephone                    : +1 800-645-5476

1. 4. Emergency telephone

Emergency Phone #      : 800-424-9300 CHEMTREC (USA) +1-703-

527-3887 CHEMTREC (International) 24

Hours/day; 7 Days/week

SECTION 2: Hazards identification

1. 1. Classification of the substance or mixture

Not a hazardous substance or mixture.

1. 2. GHS Label elements, including precautionary statements

Not a hazardous substance or mixture.

1. 3. Hazards not otherwise classified (HNOC) or not covered by GHS - none

SECTION 3: Composition/information on ingredients

3.1    Substances

Molecular weight            : 530.65 g/mol

CAS-No.                      : 24991-55-7

No components need to be disclosed according to the applicable regulations.

Millipore - 8.14171                                                                                                                        Page 1 of 8

SECTION 4: First aid measures

1. 1. De script ion of first-aid measures If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

1. 2. Most important symptoms and effects, both acute and  delay ed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

1. 3. Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

1. 1. Extinguishing media

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limit ations of extinguishing agents are given.

1. 2. Special hazards arising from the substance or mixture

Nature of decomposition products not known. Combustible.

Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.

Development of hazardous combustion gases or vapours possible in the event of fire.

1. 3. Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.

1. 4. Further information

Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

1. 1. Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Millipore - 8.14171                                                                                                                        Page 2 of 8

1. 2. Environmental precautions

Do not let product enter drains.

1. 3. Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

1. 4. Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

1. 1. Precautions for safe handling

For precautions see section 2.2.

1. 2. Conditions for safe storage, including any incompatibilities Storage conditions

Tightly closed. Dry.

Store below +30°C.

Storage class (TRGS 510): 11: Combustible Solids

1. 3. Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

1. 1. Control parameters

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

1. 2. Exposure controls

Appropriate engineering controls

Change contaminated clothing. Wash hands after working with substance.

Personal protective equipment Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: butyl-rubber

Minimum layer thickness: 0.7 mm Break through time: 480 min Material tested:Butoject® (KCL 898)

Millipore - 8.14171                                                                                                                        Page 3 of 8

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0.4 mm Break through time: 30 min

Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

1. 1. Information on basic physical and chemical properties
      1. Appearance              Form: liquid Color: colorless
      2. Odor                      No data available
      3. Odor Threshold        No data available
      4. pH                          No data available

1. 1. 5. Melting

point/freezing point

1. 1. 6. Initial boiling point and boiling range

No data available

> 250 °C > 482 °F

1. 1. 7. Flash point              254 °C (489 °F) - open cup
      8. Evaporation rate        No data available

1. 1. 1. Flammability (solid, gas)

1. 1. 10. Upper/lower flammability or explosive limit s

No data available

Lower explosion limit : 0.5 %(V)

1. 1. 11. Vapor pressure        No data available

1. 1. 50. Vapor density          No data available

1. 1. 1000. Relative density        No data available
      14. Water solubility          No data available

• • • Partition coefficient: n-octanol/water
    • Autoignition temperature

No data available No data available

Millipore - 8.14171                                                                                                                        Page 4 of 8

1. 1. 17. Decomposition temperature

No data available

1. 1. 18. Viscosity                  No data available
      19. Explosive properties  No data available
      20. Oxidizing properties    No data available
   2. Other safety information

No data available

SECTION 10: Stability and reactivity

1. 1. Reactivity

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

1. 2. Chemical stability

The product is chemically stable under standard ambient conditions (room temperature). Contains the following stabilizer(s):

butyl hydroxytoluene (BHT) (<=0.10.0999 %)

1. 3. Possibility of hazardous reactions

No data available

1. 4. Conditions to avoid

Strong heating.

1. 5. Incompatible materials

No data available

1. 6. Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

1. 1. Information on toxicological effects Acute toxicity

Acute toxicity estimate Oral - 2,525 mg/kg (Calculation method)

LD50 Oral - Rat - > 2,000 mg/kg (OECD Test Guideline 401)

Acute toxicity estimate Inhalation - 4 h - 5.3 mg/l (Calculation method)

LC50 Inhalation - Rat - 4 h - > 5.7 mg/l (OECD Test Guideline 403)

Dermal: No data available No data available

Skin corrosion/irritation

Skin - Rabbit

result : No skin irritation

Millipore - 8.14171                                                                                                                        Page 5 of 8

(OECD Test Guideline 404)

Serious eye damage/eye irritation

Eyes - Rabbit

result : No eye irritation (OECD Test Guideline 405)

Respiratory or skin sensitization

No data available

Germ cell mutagenicity

No data available

Carcinogenicity

IARC:      No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

NTP:      No ingredient of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA:    No component of this product present at levels greater than or equal to 0.1% is on OSHA’s list of regulated carcinogens.

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

1. 2. Additional Information

Not available

SECTION 12: Ecological information

1. 1. Toxicity

Toxicity to fish          LC50 - Danio rerio (zebra fish) - > 10,000 mg/l - 96 h (OECD Test Guideline 203)

Toxicity to bacteria    Remarks: (External MSDS)

(polymer of ethylene glycol, methylated)

1. 2. Persistence and degradability

Biodegradability           result : < 20 % - Not readily biodegradable.

Remarks: (External MSDS)

Chemical Oxygen Demand (COD)

1,800 mg/g

Remarks: (External MSDS)

Millipore - 8.14171                                                                                                                        Page 6 of 8

1. 3. Bioaccumulative potential

No data available

1. 4. Mobility in soil

No data available

1. 5. result s of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

1. 6. Other adverse effects

Additional ecological information

No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods Product

Waste material must be disposed of in accordance with the national and loc No mixing

with other waste. Handle uncleaned containers like the product See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

SECTION 14: Transport information DOT (US)

Not dangerous goods

IMDG

Not dangerous goods

IATA

Not dangerous goods

Further information

Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information SARA 302 Components

This material does not contain any components with a section 302 EHS TPQ.

SARA 313 Components

This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

Massachusetts Right To Know Components

No components are subject to the Massachusetts Right to Know Act.

Millipore - 8.14171                                                                                                                        Page 7 of 8