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بنزآمید 250گرمی

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بنزآمید 250گرمی
 بنزآمید 250گرمیمحصول مرک آلمانBenzamide 250g
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مشخصات

 

SAFETY DATA SHEET

according to the (US) Hazard Communication Standard (29 CFR 1910.1200)


Revision Date 10/13/2017                                                                                        Version 1.3

 

SiSECTION 1.Identification Product identifier

Product number

802191

Product name

Benzamide for synthesis

CAS-No.

55-21-0

 

Relevant identified uses of the substance or mixture and uses advised against

 

Identified uses

Chemical for synthesis

 

Detailsofthesupplierofthe safety data sheet

 

Company

EMD Millipore Corporation | 290 Concord Road, Billerica, MA 01821, United States of America | General Inquiries: +1-978-715-4321 | Monday to Friday, 9:00 AM to 4:00 PM Eastern Time (GMT-5)

MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.

 

 

Emergency telephone

800-424-9300 CHEMTREC (USA)

+1-703-527-3887 CHEMTREC (International)

24 Hours/day; 7 Days/week

Acute toxicity, Category 4, Oral, H302

Germ cell mutagenicity, Category 2, H341

 

SECTION 2. Hazards identification GHS Classification

 

For the full text of the H-Statements mentioned in this Section, see Section 16.

 

GHS-Labeling

    
  
 


Hazard pictograms

 

Signal Word

Warning

 

Hazard Statements

H302 Harmful if swallowed.

H341 Suspected of causing genetic defects.

 

Precautionary Statements

P201 Obtain special instructions before use.

 

 

P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product. P281 Use personal protective equipment as required.

P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

P330 Rinse mouth.

P405 Store locked up.

P501 Dispose of contents/ container to an approved waste disposal plant.

 

CTION 3. Composition/i Formula

nformation on ingredients

C₆H₅CONH₂                C₇H₇NO (Hill)

Molar mass

121.14 g/mol

 

Other hazards None known.

 
 

 

 

SE

 

 

 

Hazardous ingredients

Chemicalname(Concentration)

CAS-No.

benzamide (>= 90 % - <= 100 % )

55-21-0

Exact percentages are being withheld as a trade secret.

SECTION 4. First aid measures De script ionoffirst-aid measures

Inhalation

After inhalation: fresh air. Call in physician.

Skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

Eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

Ingestion

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Never give anything by mouth to an unconscious person.

Most important symptoms and effects, both acute and  delay ed

irritant effects, muscular weakness, impaired vision and hearing defect

 

Indication of any immediate medical attention and special treatment needed No information available.

SECTION5.Fire-fightingmeasures Extinguishing media

 

 

Suitable extinguishing media

Water, Foam, Carbon dioxide (CO2), Dry powder

Unsuitable extinguishing media

For this substance/mixture no limit ations of extinguishing agents are given.

 

Special hazards arising from the substance or mixture

Combustible.

Forms explosive mixtures with air on intense heating.

Vapors are heavier than air and may spread along floors.

Development of hazardous combustion gases or vapors possible in the event of fire.

Fire may cause evolution of:

nitrogen oxides

Advice for firefighters

Special protective equipment for fire-fighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

 
 

 

 

SECTION 6. Accidental release measures

Personalprecautions,protectiveequipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

Advice for emergency responders:

Protective equipment see section 8.

 

Environmental precautions

Do not let product enter drains.

 

Methods and materials for containment and cleaning up

Observe label precautions.

Work under hood. Do not inhale substance/mixture.

 

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

 
 

 

 

SECTION 7. Handling and storage Precautions for safe handling

 

 

Conditions for safe storage, including any incompatibilities

Tightly closed. Dry.

Store below +30°C (+86°F).

 

 

 

 

SECTION 8. Exposure controls/personal protection Exposure limit (s)

Contains no substances with occupational exposure limit values.

Engineering measures

Technical measures and appropriate working operations should be given priority over the use of personal protective equipment.

Individual protection measures

Protective clothing should be select ed specifically for the workplace, depending on concentration and quantity of the hazardous substances handled. The chemical resistance of the protective equipment should be inquired at the respective supplier.

Hygiene measures

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

Eye/face protection

Safety glasses

Hand protection

full contact:

 

Glove material:

Nitrile rubber

Glove thickness:

0.11 mm

Break through time:

> 480 min

splash contact:

 

Glove material:

Nitrile rubber

Glove thickness:

0.11 mm

Break through time:

> 480 min

The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril® L (full contact), KCL 741 Dermatril® L (splash contact).

The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types.

This recommendation applies only to the product stated in the safety data sheet and supplied by us as well as to the purpose specified by us. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Other protective equipment:

protective clothing

Respiratory protection

required when dusts are generated.

Recommended Filter type: Filter P 3 (acc. to DIN 3181) for solid and liquid particles of toxic and very toxic substances

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are performed according to the instructions of the producer. These measures have to be properly documented.

 

 

 

 

CTION 9. Physical and che Physical state

mical properties

crystalline

 

SE

 

 

Color

white

 

Odor

weak ammoniacal

 

Odor Threshold

No information available.

 

pH

6.9

(saturated solution)

Melting point/range

255 - 261 °F (124 - 127 °C)

 

 

Boiling point

No information available.

Flash point

356 °F (180 °C)

Method: c.c.

 

Evaporation rate

No information available.

 

Flammability (solid, gas)

No information available.

 

Lower explosion limit

No information available.

 

Upper explosion limit

No information available.

 

Vapor pressure

0.000056 hPa

at 68 °F (20 °C)

Relative vapor density

No information available.

Density

1.34 g/cm3

at 68 °F (20 °C)

Relative density

No information available.

 

Water solubility

13 g/l

at 77 °F (25 °C)

Partition coefficient: n- octanol/water

log Pow: 0.64 (experimental)

Bioaccumulation is not expected. (Lit.)

Autoignition temperature

No information available.

Decomposition temperature

> 554 °F (> 290 °C)

 

 

Viscosity, dynamic

 

No information available.

Explosive properties

Not classified as explosive.

 

Oxidizing properties

none

 

Ignition temperature

> 932 °F (> 500 °C)

Method: DIN 51794

 

Bulk density

550 kg/m3

 

 
 

 

 

SECTION 10. Stability and reactivity Reactivity

 

 

 

 

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be

assumed.

 

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature).

 

Possibility of hazardous reactions

Violent reactions possible with:

Strong oxidizing agents

Conditions to avoid Strong heating.

 

Incompatible materials

no information available

 

Hazardous decomposition products in the event of fire: See section 5.

 
 

 

 

SECTION 11. Toxicological information Information on toxicological effects

Likely route of exposure

Eye contact, Skin contact, Ingestion

Acuteoraltoxicity

LD50 Rat: 1,125 mg/kg (External MSDS)

Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.

Acute inhalation toxicity

 

Symptoms: Possible damages:, Irritation symptoms in the respiratory tract., Lung edema

 

 

Skin irritation

Rabbit

result : No irritation (External MSDS)

Eye irritation

Rabbit

result : slight irritation (External MSDS)

Genotoxicityin vitro

Mutagenicity (mammal cell test): micronucleus.

result : positive (External MSDS)

CMR effects

Mutagenicity:Suspected of causing genetic defects.

Specific target organ systemic toxicity - single exposure

The substance or mixture is not classified as specific target organ toxicant, single exposure.

Specific target organ systemic toxicity - repeated exposure

The substance or mixture is not classified as specific target organ toxicant, repeated exposure.

Aspiration hazard

Regarding the available data the classification criteria are not fulfilled.

Carcinogenicity

 

IARC

No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed

human carcinogen by IARC.

OSHA

No component of this product present at levels greater than or

equal to0.1%isonOSHAslistofregulatedcarcinogens.

NTP

No ingredient of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen

by NTP.

ACGIH

No ingredient of this product present at levels greater than or

equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.

 

Further information

Possible effect after contact with substance:

impaired vision and hearing defect, muscular weakness

Other dangerous properties can not be excluded.

Handle in accordance with good industrial hygiene and safety practice.

SECTION 12. Ecological information Ecotoxicity

Toxicity to fish

LC50 Pimephales promelas (fathead minnow): 661 mg/l; 96 h (ECOTOX database )

 

 

Toxicity to bacteria

EC0 Pseudomonas putida: 1,000 mg/l(External MSDS)

Persistence and degradability

Biodegradability

> 75 %

OECD Test Guideline 301D Readily biodegradable.

Bioaccumulativepotential

Partition coefficient: n-octanol/water

log Pow: 0.64 (experimental)

Bioaccumulation is not expected. (Lit.)

Mobility in soil

No information available.

Additional ecological information

Discharge into the environment must be avoided.

 

 
 

 

 

SECTION 13. Disposal considerations

The information presented only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. Disposal should be in accordance with applicable regional, national and local laws and regulations.

 
 

 

 

SECTION 14. Transport information Land transport (DOT)

Not classified as dangerous in the meaning of transport regulations.

 

Air transport (IATA)

Not classified as dangerous in the meaning of transport regulations.

 

Sea transport (IMDG)

Not classified as dangerous in the meaning of transport regulations.

 
 

 

 

SECTION 15. Regulatory information United States of America

SARA 313

The following components are subject to reporting levels established by SARA Title III, Section 313:

Ingredients

benzamide

55-21-0

100 %

SARA 302

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

 

 

Clean Water Act

This product does not contain any Hazardous Substances listed under the U.S. CleanWater Act, Section 311, Table 116.4A.

This product does not contain any Hazardous Chemicals listed under the U.S. CleanWater Act, Section 311, Table 117.3.

DEA List I Not listed

DEA List II Not listed

US State Regulations Massachusetts Right To Know

Ingredients

benzamide

Pennsylvania Right To Know

Ingredients

benzamide

New Jersey Right To Know

Ingredients

benzamide

California Prop 65 Components

This product does not contain any chemicals known to the State of California to cause cancer, birth, or any other reproductive defects.

Notification status

TSCA:

All components of the product are listed in the TSCA-inventory.

DSL:

All components of this product are on the Canadian DSL

 

SECTION 16. Other information Training advice

Provide adequate information, instruction and training for operators.

 

Labeling

    
  
 


Hazard pictograms

 

Signal Word

Warning

 

 

 

Hazard Statements

H302 Harmful if swallowed.

H341 Suspected of causing genetic defects.

 

Precautionary Statements

Response

P308 + P313 IF exposed or concerned: Get medical advice/ attention.

 

Full text of H-Statements referred to under sections 2 and 3.

 

H302

Harmful if swallowed.

H341

Suspected of causing genetic defects.

 

Key or legend to abbreviations and acronyms used in the safety data sheet Used abbreviations and acronyms can be looked up at www.wikipedia.org.

 

Revision Date10/13/2017

 
 

 

 

The information contained herein is based on the present state of our knowledge. It characterizes the product with regard to appropriate safety precautions. It does not represent a warranty of any product properties and we assume no liability for any loss or injury which may result   from the use of this information. Users should conduct their own investigations to determine the suitability of the information.

All rights reserved. Millipore and the MMark are registered trademarks of Merck KGaA, Darmstadt, Germany.

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