SAFETY DATA SHEET
according to the (US) Hazard Communication Standard (29 CFR 1910.1200)
Revision Date 10/13/2017 Version 1.3
SiSECTION 1.Identification Product identifier
Product number | 802191 |
Product name | Benzamide for synthesis |
CAS-No. | 55-21-0 |
Relevant identified uses of the substance or mixture and uses advised against
Identified uses | Chemical for synthesis |
Detailsofthesupplierofthe safety data sheet
Company | EMD Millipore Corporation | 290 Concord Road, Billerica, MA 01821, United States of America | General Inquiries: +1-978-715-4321 | Monday to Friday, 9:00 AM to 4:00 PM Eastern Time (GMT-5) MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany. |
Emergency telephone | 800-424-9300 CHEMTREC (USA) +1-703-527-3887 CHEMTREC (International) 24 Hours/day; 7 Days/week |
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SECTION 2. Hazards identification GHS Classification
For the full text of the H-Statements mentioned in this Section, see Section 16.
GHS-Labeling
Signal Word
Warning
H302 Harmful if swallowed.
H341 Suspected of causing genetic defects.
P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product. P281 Use personal protective equipment as required.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
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Other hazards None known.
SE
Hazardous ingredients
Chemicalname(Concentration) |
CAS-No. |
benzamide (>= 90 % - <= 100 % ) |
55-21-0 |
Exact percentages are being withheld as a trade secret. |
SECTION 4. First aid measures De script ionoffirst-aid measures
After inhalation: fresh air. Call in physician.
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Never give anything by mouth to an unconscious person.
Most important symptoms and effects, both acute and delay ed
irritant effects, muscular weakness, impaired vision and hearing defect
Indication of any immediate medical attention and special treatment needed No information available.
SECTION5.Fire-fightingmeasures Extinguishing media
Water, Foam, Carbon dioxide (CO2), Dry powder
For this substance/mixture no limit ations of extinguishing agents are given.
Special hazards arising from the substance or mixture
Combustible. |
Forms explosive mixtures with air on intense heating. |
Vapors are heavier than air and may spread along floors. |
Development of hazardous combustion gases or vapors possible in the event of fire. |
Fire may cause evolution of: |
nitrogen oxides |
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
SECTION 6. Accidental release measures
Personalprecautions,protectiveequipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. |
Advice for emergency responders: |
Protective equipment see section 8. |
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
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Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
SECTION 7. Handling and storage Precautions for safe handling
Conditions for safe storage, including any incompatibilities
Tightly closed. Dry. |
Store below +30°C (+86°F). |
SECTION 8. Exposure controls/personal protection Exposure limit (s)
Contains no substances with occupational exposure limit values.
Engineering measures
Technical measures and appropriate working operations should be given priority over the use of personal protective equipment.
Individual protection measures
Protective clothing should be select ed specifically for the workplace, depending on concentration and quantity of the hazardous substances handled. The chemical resistance of the protective equipment should be inquired at the respective supplier.
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
Safety glasses
full contact: |
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Glove material: | Nitrile rubber |
Glove thickness: | 0.11 mm |
Break through time: | > 480 min |
splash contact: |
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Glove material: | Nitrile rubber |
Glove thickness: | 0.11 mm |
Break through time: | > 480 min |
The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374, for example KCL 741 Dermatril® L (full contact), KCL 741 Dermatril® L (splash contact).
The breakthrough times stated above were determined by KCL in laboratory tests acc. to EN374 with samples of the recommended glove types.
This recommendation applies only to the product stated in the safety data sheet and supplied by us as well as to the purpose specified by us. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
protective clothing
required when dusts are generated.
Recommended Filter type: Filter P 3 (acc. to DIN 3181) for solid and liquid particles of toxic and very toxic substances
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are performed according to the instructions of the producer. These measures have to be properly documented.
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SE
Color | white |
Odor | weak ammoniacal |
Odor Threshold | No information available. |
pH | 6.9 (saturated solution) |
Melting point/range | 255 - 261 °F (124 - 127 °C) |
Boiling point | No information available. |
Flash point | 356 °F (180 °C) Method: c.c. |
Evaporation rate | No information available. |
Flammability (solid, gas) | No information available. |
Lower explosion limit | No information available. |
Upper explosion limit | No information available. |
Vapor pressure | 0.000056 hPa at 68 °F (20 °C) |
Relative vapor density | No information available. |
Density | 1.34 g/cm3 at 68 °F (20 °C) |
Relative density | No information available. |
Water solubility | 13 g/l at 77 °F (25 °C) |
Partition coefficient: n- octanol/water | log Pow: 0.64 (experimental) Bioaccumulation is not expected. (Lit.) |
Autoignition temperature | No information available. |
Decomposition temperature | > 554 °F (> 290 °C) |
Viscosity, dynamic |
No information available. |
Explosive properties | Not classified as explosive. |
Oxidizing properties | none |
Ignition temperature | > 932 °F (> 500 °C) Method: DIN 51794 |
Bulk density | 550 kg/m3 |
SECTION 10. Stability and reactivity Reactivity
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Chemical stability
The product is chemically stable under standard ambient conditions (room temperature).
Possibility of hazardous reactions
Violent reactions possible with: |
Strong oxidizing agents |
Conditions to avoid Strong heating.
Incompatible materials
no information available
Hazardous decomposition products in the event of fire: See section 5.
SECTION 11. Toxicological information Information on toxicological effects
Eye contact, Skin contact, Ingestion
LD50 Rat: 1,125 mg/kg (External MSDS)
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Symptoms: Possible damages:, Irritation symptoms in the respiratory tract., Lung edema
Rabbit
result : No irritation (External MSDS)
Rabbit
result : slight irritation (External MSDS)
Mutagenicity (mammal cell test): micronucleus.
result : positive (External MSDS)
Mutagenicity:Suspected of causing genetic defects.
The substance or mixture is not classified as specific target organ toxicant, single exposure.
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Regarding the available data the classification criteria are not fulfilled.
Carcinogenicity
IARC | No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. |
OSHA | No component of this product present at levels greater than or equal to0.1%isonOSHA’slistofregulatedcarcinogens. |
NTP | No ingredient of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. |
ACGIH | No ingredient of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. |
Further information
Possible effect after contact with substance: |
impaired vision and hearing defect, muscular weakness |
Other dangerous properties can not be excluded. |
Handle in accordance with good industrial hygiene and safety practice. |
SECTION 12. Ecological information Ecotoxicity
LC50 Pimephales promelas (fathead minnow): 661 mg/l; 96 h (ECOTOX database )
EC0 Pseudomonas putida: 1,000 mg/l(External MSDS)
Persistence and degradability
> 75 %
OECD Test Guideline 301D Readily biodegradable.
Bioaccumulativepotential
log Pow: 0.64 (experimental)
Bioaccumulation is not expected. (Lit.)
Mobility in soil
No information available.
Discharge into the environment must be avoided.
SECTION 13. Disposal considerations
The information presented only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. Disposal should be in accordance with applicable regional, national and local laws and regulations.
SECTION 14. Transport information Land transport (DOT)
Not classified as dangerous in the meaning of transport regulations.
Air transport (IATA)
Not classified as dangerous in the meaning of transport regulations.
Sea transport (IMDG)
Not classified as dangerous in the meaning of transport regulations.
SECTION 15. Regulatory information United States of America
SARA 313
The following components are subject to reporting levels established by SARA Title III, Section 313:
benzamide | 55-21-0 | 100 % |
SARA 302
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
Clean Water Act
This product does not contain any Hazardous Substances listed under the U.S. CleanWater Act, Section 311, Table 116.4A.
This product does not contain any Hazardous Chemicals listed under the U.S. CleanWater Act, Section 311, Table 117.3.
DEA List I Not listed
DEA List II Not listed
US State Regulations Massachusetts Right To Know
benzamide
benzamide
benzamide
This product does not contain any chemicals known to the State of California to cause cancer, birth, or any other reproductive defects.
Notification status
TSCA: | All components of the product are listed in the TSCA-inventory. |
DSL: | All components of this product are on the Canadian DSL |
Provide adequate information, instruction and training for operators.
Labeling
Signal Word
Warning
H302 Harmful if swallowed.
H341 Suspected of causing genetic defects.
Response
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
Full text of H-Statements referred to under sections 2 and 3.
H302 | Harmful if swallowed. |
H341 | Suspected of causing genetic defects. |
Key or legend to abbreviations and acronyms used in the safety data sheet Used abbreviations and acronyms can be looked up at www.wikipedia.org.
Revision Date10/13/2017
The information contained herein is based on the present state of our knowledge. It characterizes the product with regard to appropriate safety precautions. It does not represent a warranty of any product properties and we assume no liability for any loss or injury which may result from the use of this information. Users should conduct their own investigations to determine the suitability of the information.
All rights reserved. Millipore and the “M” Mark are registered trademarks of Merck KGaA, Darmstadt, Germany.
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